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br Materials and Methods br Results br Discussion
2018-11-14
Materials and Methods Results Discussion The prophylactic tolerance protocol entails the administration of immunosuppressive drugs. Rapamycin is an mTOR inhibitor approved for immunosuppression in organ transplantation (and is commonly used in children (Ganschow et al., 2013)) and has poten
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Antibodies represent one the most effective tools to fight
2018-11-14
Antibodies represent one the most effective tools to fight invading pathogens used by the immune system. By binding to specific epitopes on virus and bacteria they can neutralize toxins, activate complement and enhance phagocytic clearance. Some Senexin B also bind self-antigens helping to clear aw
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SAR405 The level of estrogens is age dependent in females wh
2018-11-14
The level of estrogens is age-dependent in females, whereas the SAR405 of BMP4 might be influenced by genetics and may be highly variable among humans. It was reported that one genetic variant of BMP4 (single nucleotide polymorphism rs8014363) was associated with levels of triglyceride and high-dens
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A technique recently developed for
2018-11-14
A technique recently developed for in vitro amplification of prions, the RT-QuIC (quaking-induced conversion) assay, is a highly sensitive and specific technique that can detect small amounts of prion-seeding activity (Takatsuki et al., 2015). In our study, the detection limit of the RT-QuIC assay w
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Intramuscular IM oxytocin international units
2018-11-14
Intramuscular (IM) Tacrolimus (10 international units [IU]) was identified as one of 13 life-saving commodities for women and children in a 2012 United Nations (UN) Commission Report (United Nations, 2012), and was included in the World Health Organization (WHO) model list of essential medicines (W
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The classical approach for the assessment of
2018-11-14
The classical approach for the assessment of an environmental carcinogen consists of both experimental and epidemiological investigations. On the experimental front, existing studies have focused on the effects of aluminium on cultured mammary epithelial cells. Concentrations of aluminium in the ran
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Given the marked and well documented developmental changes i
2018-11-14
Given the marked, and well-documented developmental changes in SP600125 structure during adolescence, investigation of structural brain development, and its relation to the emergence of dispositional mindfulness during adolescence, is of interest. Cortical grey matter has been documented to follow
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Experimental procedures br Results br Discussion Between gro
2018-11-14
Experimental procedures Results Discussion Between-groups differences in pattern of activity in the l-MFG and r-MFG were largest in the two experimental conditions in which feedback was not available. The MFG is a D-Luciferin cost region known to be normally involved in working memory and to
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Glu neurotransmission is contingent upon successful Gln Glu
2018-11-14
Glu neurotransmission is contingent upon successful Gln-Glu cycling in the brain, perhaps increasing the combined functional relevance of these related metabolites as compared to either metabolite examined alone (Yüksel and Öngür, 2010). In this metabolic pathway, Glu that is released into the synap
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Aberrant patterns of substance use have long
2018-11-14
Aberrant patterns of substance use have long been recognized as a significant clinical and public health problem. Among adults, substance use problems are quite common (). Recent surveys indicate that 7.8% of U.S. adults over the age of 18 had one or more substance use disorders in the past year (),
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A growing body of literature suggests
2018-11-14
A growing body of literature suggests that Major Depressive Disorder (MDD) is associated with impaired cognitive control processes necessary for effective emotion regulation (Diener et al., 2012). These impairments are often coupled with ineffective or maladaptive regulation strategies that may exac
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br A view of late hippocampal development predictions
2018-11-14
A view of late hippocampal development: predictions One prediction is that children relying on cortical networks should require many more exposures for learning and retain less. An excellent example comes from word learning. Bergelson and Swingley (2012) report that by 6–9 months of age children
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br Analysis Percentages were calculated for the
2018-11-13
Analysis Percentages were calculated for the SIP׳s 12 categories, two dimensions, independent categories not included in the two dimensions, and overall score. Results were examined for all patients with a physician diagnosis of narcolepsy, the subgroups with and without cataplexy, and the subgro
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The technology used in this work is
2018-11-13
The technology used in this work is based on electrolyte–insulator–semiconductor (EIS) biosensors. EIS vary their potential because of a detection event at the insulator/electrolyte interface. For this structure, capacitance vs voltage (CV) measurements provide information on the interface potential
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br Results and discussion The switching
2018-11-13
Results and discussion The switching acceleration for each of several switches is shown in Fig. 6 for the “cut and bend” design, and in Fig. 7 for the molded design. Each switch was left in the stressed stable state (shown in Figs. 3b and 5b) for a urokinase of 2–3weeks, and each was tested seve
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