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Paying now rather than forever has never been
2019-04-24
Paying now rather than forever has never been as relevant as a global health solution to the HIV pandemic than in 2013. The relative success of the ongoing replenishment session for the Global Fund is a positive signal, although still insufficient considering the evidence-based targets that are set
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Do ponto de vista da insurg ncia a
2019-04-24
Do ponto de vista da insurgência, jnk inhibitor resposta governamental se encaixava perfeitamente à leitura política sustentada por Guzmán. O “presidente” pregava que a ação senderista explicitaria a violência estatal, constrangendo o campesinato a se levantar contra o Estado e em última análise, to
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Sin embargo la mayor a de los aventureros se qued
2019-04-24
Sin embargo, la mayoría de los aventureros se quedó en la ensoñación, pues no logró hacerse de caudales, ni alcanzó encomiendas; de hecho, hacia 1540 y aun años después, el número de encomenderos en el gran Perú (hoy Perú, Bolivia y Ecuador) jamás rebasó los 500, indudablemente una minoría de la pob
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India is the second largest
2019-04-23
India is the second largest consumer and third largest producer of tobacco in the world. The Indian Government has been significantly engaged in addressing the tobacco problem. A major policy, the Cigarettes and Other Tobacco Products Act (COTPA) was implemented in 2003, followed by WHO\'s Framework
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The exhibited efficacies of bone
2019-04-23
The exhibited efficacies of bone targeting treatments, in phase III clinical trials, suggest significant progress in delaying skeletal-related events, with improvements having been seen in the direct comparisons between generations of drugs. These findings also lend clear support to the utility of b
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Certainly dynamic interactions between DTCs and stromal
2019-04-23
Certainly, dynamic interactions between DTCs and stromal order EPZ-6438 within the bone microenvironment disrupt bone homeostasis, which is normally tightly controlled, to fuel metastatic progression [18] (Table 1). For example, it is well established that osteolytic breast cancer DTC-derived facto
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La Constituci n espa ola de dispone
2019-04-23
La Constitución española de 1812 dispone bajo el nombre de América septentrional un territorio que desde California, Nuevo México y Texas hasta la Capitanía de Guatemala conforma una inmensa, compleja y rica estructura administrativa. Guatemala se separa poco antes de la jura de la Constitución de 1
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It must be noted that
2019-04-23
It must be noted that modern physical techniques for structural analysis of steroids were not available to these early talented scientists that time. It was a challenging task for these early scientists to precisely identify the chemical structures of cholesterol and bile acids. However, the develop
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To the best of our
2019-04-23
To the best of our knowledge, only one other group studied low-dose protracted oral clofarabine in MDS patients who failed hypomethylating agents. They studied 5mg (fixed dose) daily for 10 consecutive days of a 28-day cycle. All patients who were treated for 10 days had a greater than 25% drop in
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aspirin solubility In MM the optimal sequence or combination
2019-04-23
In MM, the optimal sequence or combination of the different therapeutic regimens available remains unclear and information is needed on the efficacy of each treatment after various prior therapies. Although a substantial number of different regimens and schedules were used for the treatment of first
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Discussion Previous study has shown that
2019-04-23
Discussion Previous study has shown that one of the most important characteristics of music is that of reducing anxiety. The mechanism of music therapy is thought to arise from multiple nervous stimuli that are conducted into the brain, which are antagonists to each other, and under certain conditi
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br Case A year old Caucasian male
2019-04-22
Case 4 A 59 year old Caucasian male with a history of chronic renal insufficiency was transferred to our intensive care unit from an outside hospital, intubated secondary to respiratory failure and severe mucositis. He arrived on multiple broad spectrum LDN193189 for treatment of healthcare asso
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br We sincerely appreciate the comment by Lombardi
2019-04-22
We sincerely appreciate the comment by Lombardi et al on our published paper. demonstrates the incidence of dyspnea and the discontinuation of ticagrelor due to dyspnea in patients who reported dyspnea in Phase 3/4 clinical trials of acute coronary syndrome with available relevant data. Our study
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Table shows the AF ablation procedure data
2019-04-22
Table 2 shows the AF ablation procedure data. The preoperative inspection consisted of transesophageal echocardiography and cardiac computed tomography (CT) in 79.9% and 80.8%, respectively; cardiac magnetic resonance imaging (MRI) was performed in only 1.1% of the patients. Two 3D mapping systems w
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Approximately of the patients who developed
2019-04-22
Approximately 50% of the patients who developed BM during their palliative disease course received BM-related radiotherapy and/or surgery; 12% of the patients received both therapy options. Our data confirms that the majority of patients with BM will respond to a low course of radiotherapy with good
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