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Consistent with our previous study Gao
2020-11-16
Consistent with our previous study (Gao et al., 2018b; Wu et al., 2018), we found that TCB-2 disrupted both pup preference and home-cage maternal behavior. Based on the findings that 4-h pup SBHA supplier synthesis (a technique presumably increases maternal motivation) failed to attenuate the TCB-2-
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br Development of the double strand break
2020-11-16
Development of the double strand break repair model for meiotic recombination Meiotic recombination was first described by Frans Alfons Janssens using lpl receptor in the salamander Batracoseps attenuatus in 1909 [21] and then further elaborated at the genetic level in Drosophila by Thomas H. Mo
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Acknowledgments We acknowledge the Danish
2020-11-16
Acknowledgments We acknowledge the Danish Council for Independent Research (Grant no. 11-105250) and the Carlsberg Foundation (Grant no. 2011-01-0567) for funding this work. Introduction DNA is vital as a biological target to design diagnostic agents as well as therapeutic drugs. The recognitio
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In conclusion we have recombinantly expressed and
2020-11-16
In conclusion, we have recombinantly expressed and purified the product of the YP_002262821.1 gene from A. salmonicida and confirmed that it possesses ATP-dependent DNA ligase activity. Comparison of the full-length and truncated versions of the protein indicate that the N-terminal 25 dpp-4 inhibito
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actin polymerization inhibitor br Rationale and Conventional
2020-11-16
Rationale and Conventional Use of Alkylating Agents and Platinum Derivatives in Clinical Practice After the attack on Bari Harbor in 1943 revealed the effects of mustard gas on bone marrow depletion and the first therapeutic outcomes in lymphoma, alkylating agents gradually became a gold standard
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Third DGK protein stabilization by myristic
2020-11-16
Third, DGKδ2 protein stabilization by myristic 3X FLAG tag Peptide receptor is cell line specific. Myristic acid had no obvious effects on DGKδ protein stability in the liver cell line HepG2, pancreas cell line MIA-PaCa-2 and neuronal cell line Neuro-2a cells (Fig. 5). Although myristic acid modera
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br Contributors br Acknowledgements br Introduction Pemphigu
2020-11-16
Contributors Acknowledgements Introduction Pemphigus disorders are characterized by autoantibodies binding to desmosomes between epidermal cells, resulting in the loss of cell to cell adhesion and blister formation. In pemphigus foliaceus, autoantibodies predominantly bind to desmoglein 1,
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RO4987655 Similar to Bdnf acute administration of RG did not
2020-11-16
Similar to Bdnf4, acute administration of RG108 did not alter gene expression of Gria1 and Hdac2, despite their relevance for the task. Gria1 belongs to the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic RO4987655 receptor (AMPAR) family that is known to be crucial for LTP and the strengthening of
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Cryoprotectant equilibration and the response to ice concent
2020-11-16
Cryoprotectant equilibration and the response to ice concentrated media are the two facets of cellular cryobiological protocols most commonly covered by mathematical modeling. In these models, Triclosan australia are typically assumed to have uniform, spatially independent extracellular concentrati
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br Atypical collagen glycosylation The disaccharide Glc
2020-11-16
Atypical collagen glycosylation The disaccharide Glc(α1-2)Gal(β1-O) decorating collagens is strongly conserved across the animal kingdom, yet for every rule, nature provides exceptions. The deep-sea worm Riftia pachyptila of the phylum Annelida represents an intriguing exception. R. pachyptila is
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Case report The patient was referred to
2020-11-14
Case report The patient was referred to the oral and maxillofacial department at the authors’ institution for further evaluation and treatment. The patient underwent tumor resection with left hemi-mandibulectomy with wide bony margins (Fig. 1A), and mandible reconstruction with fibula free flap and
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MSCs are self renewing multipotent progenitor
2020-11-14
MSCs are self-renewing, multipotent progenitor cells, with multilineage potential to differentiate into adipocytes, osteocytes, and chondrocytes. In addition, MSCs can migrate to sites of inflammation, supporting hematopoiesis and homeostatic maintenance. Given their unique therapeutic properties, M
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Introduction Neuropathic pain occurs in approximately one
2020-11-14
Introduction Neuropathic pain occurs in approximately one-third of patients with diabetes and is refractory to currently available analgesic drugs (Abbott et al., 2011). This painful diabetic neuropathy (PDN) is associated with elevated levels of methylglyoxal (MG; a reactive glucose metabolite) an
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Cy7 NHS ester Prostanoids typically act in an autocrine
2020-11-14
Prostanoids typically act in an autocrine and paracrine fashion by binding to specific receptors in target Cy7 NHS ester and there is evidence that both PGE2 and prostacyclin may be required for the optimal activation of angiogenesis (Hata and Breyer, 2004). PGE2 and prostacyclin bind to their speci
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Ultrasound is an acoustic wave with a frequency
2020-11-14
Ultrasound is an acoustic wave with a frequency >20 kHz that needs a medium to propagate [20]. Accompanied by the spread of an ultrasonic wave, a series of alternating cycles of compression and rarefaction emerge in the liquid medium. During the rarefaction cycle, microbubbles are formed because of
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