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To the best of our
2019-04-23

To the best of our knowledge, only one other group studied low-dose protracted oral clofarabine in MDS patients who failed hypomethylating agents. They studied 5mg (fixed dose) daily for 10 consecutive days of a 28-day cycle. All patients who were treated for 10 days had a greater than 25% drop in
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aspirin solubility In MM the optimal sequence or combination
2019-04-23

In MM, the optimal sequence or combination of the different therapeutic regimens available remains unclear and information is needed on the efficacy of each treatment after various prior therapies. Although a substantial number of different regimens and schedules were used for the treatment of first
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Discussion Previous study has shown that
2019-04-23

Discussion Previous study has shown that one of the most important characteristics of music is that of reducing anxiety. The mechanism of music therapy is thought to arise from multiple nervous stimuli that are conducted into the brain, which are antagonists to each other, and under certain conditi
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br Case A year old Caucasian male
2019-04-22

Case 4 A 59 year old Caucasian male with a history of chronic renal insufficiency was transferred to our intensive care unit from an outside hospital, intubated secondary to respiratory failure and severe mucositis. He arrived on multiple broad spectrum LDN193189 for treatment of healthcare asso
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br We sincerely appreciate the comment by Lombardi
2019-04-22

We sincerely appreciate the comment by Lombardi et al on our published paper. demonstrates the incidence of dyspnea and the discontinuation of ticagrelor due to dyspnea in patients who reported dyspnea in Phase 3/4 clinical trials of acute coronary syndrome with available relevant data. Our study
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Table shows the AF ablation procedure data
2019-04-22

Table 2 shows the AF ablation procedure data. The preoperative inspection consisted of transesophageal echocardiography and cardiac computed tomography (CT) in 79.9% and 80.8%, respectively; cardiac magnetic resonance imaging (MRI) was performed in only 1.1% of the patients. Two 3D mapping systems w
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Approximately of the patients who developed
2019-04-22

Approximately 50% of the patients who developed BM during their palliative disease course received BM-related radiotherapy and/or surgery; 12% of the patients received both therapy options. Our data confirms that the majority of patients with BM will respond to a low course of radiotherapy with good
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Antenatal corticosteroids induce fetal lung maturation throu
2019-04-22

Antenatal corticosteroids induce fetal lung maturation through the same biological mechanism in low-income settings as in high-income settings and reduce the need for neonatal mechanical ventilation. Although antenatal corticosteroids might not be a so-called magic bullet as a standalone vertical in
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Obesity is not the only concern documented for
2019-04-22

Obesity is not the only concern documented for BPA. Epidemiological studies have identified neurocognitive effects of BPA and newly incident coronary artery disease, and laboratory studies strongly suggest BPA is an ovarian toxicant. The rapidly rising evidence of adverse effects has prompted manufa
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Is this perhaps a manifestation of the unequal distribution
2019-04-20

Is this perhaps a manifestation of the unequal distribution of growth, reflecting a pattern whereby income increases over the past two decades have benefited only the better-off? The evidence suggests that this is unlikely: across countries, Vollmer and colleagues report similar associations between
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Finally it is highly interesting to
2019-04-20

Finally, it is highly interesting to note that human endogenous retroviruses have been suggested to play a role in the etiology of both MS and MPN [7,9]. Supporting this notion, both MS and MPN are treated with type 1 interferons, which have very potent antiviral and immunomodulating effects. Indeed
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br OPG RANK and RANKL contribute to the
2019-04-20

OPG, RANK and RANKL contribute to the vicious cycle established between tumour pregnane x receptor and bone microenvironment: evidences for sarcomas and carcinomas RANK/RANKL axis is involved in the tumorigenic process RANK/RANKL axis is associated with the bone metastastic process, and as se
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mCAP br Conclusions br Conflict of interest br Introduction
2019-04-20

Conclusions Conflict of interest Introduction Radiofrequency (RF) catheter ablation is an established method of therapy for symptomatic supraventricular tachycardia (SVT). It has gained widespread acceptance for the treatment of accessory pathways in pediatric SVTs [1]. Accessory pathways a
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En cualquier caso sabemos que esta pol tica admonitoria del
2019-04-20

En cualquier caso, sabemos que esta política admonitoria del Corpus obtuvo resultados abundantes que refrendaron la inserción beneficiosa de altas dosis de tremendismo en una catequesis ya no necesariamente diáfana. Incluso contamos con las huellas de una recepción defectuosa del sacramento que llev
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Asimismo y con distinto nfasis entre
2019-04-20

Asimismo y con distinto énfasis entre sí, estas crónicas presentan la dimensión de la escritura de la historia como reparación, como sutura del trauma, y también como espacio textual único para la supervivencia de memorias en constante proceso de desaparición. Esto les confiere cierto ubicuo tono de
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