• br Conclusion br Experimental br Background Cancer is

  2018-10-29

  

  Conclusion Experimental Background Cancer is perhaps the most progressive and devastating disease posing a threat of mortality to the entire world despite significant advances in medical technology for its diagnosis and treatment. Recently, wide arrays of phenolic substances, particularly t

• br Declaration of interest br Ethical

  2018-10-29

  

  Declaration of interest Ethical approval Informed consent Acknowledgments The present study was funded by the Institute Of Medical Genetics College Of Life Science, Sichuan University, China. Introduction With the advancement of technologies, laboratory medicine and the need of routi

• br Interactions between contextual elements and operational

  2018-10-29

  

  Interactions between contextual elements and operational mode; the ICFs as an analytical framework Between architectural and architecture – engineering firms: similarities and differences Conclusion Introduction Mediating devices are essential tools to describe architectural designs and

• br Hypothesis of mtDNA instability in Warburg

  2018-10-29

  

  Hypothesis of mtDNA instability in Warburg effect One of the most commonly adopted hypothesis to explain the association between human mtDNA instability and Warburg effect in human cancers is oxidative damage and its vicious cycle. As we know, oxidative DNA damage has been demonstrated to play an

• Although most people with urolithiasis are

  2018-10-29

  

  Although most people with urolithiasis are treated effectively, approximately 40% experience recurrence, with some experiencing relapse up to five times. In Taiwan, the stone recurrence rate is 6.12% for the 1st year, but this rate increases to 34.71% within the first 5 years. Our data show that pat

• tsa trichostatin br Conflict of interest br Acknowledgement

  2018-10-29

  

  Conflict of interest Acknowledgement Introduction Chicken meat is favoured by consumers around the world because of its desirable nutritional qualities, such as a low fat content and a relatively high concentration of polyunsaturated fatty acids [1]. Fresh meat products are usually marketed

• glycine receptors br Experimental Procedures br Acknowledgme

  2018-10-29

  

  Experimental Procedures Acknowledgments This work was supported by funding from glycine receptors ICR . F.B.A. was supported by the Erasmus Work Placement Programme. We thank Drs. Taiping Chen (MD Anderson Cancer Center) for providing J1 WT and Dnmt1-null ESCs and Masaki Okano (Riken) for prov

• All of these studies categorize

  2018-10-26

  

  All of these studies categorize MET as an initial event during reprogramming which is followed by upregulation of the pluripotency machinery later in the process. Here we observed that in the time course of reprogramming human fibroblasts to iPSCs, the MET was preceded by a six day period (D0–6), du

• br Materials and methods br Author disclosure statement

  2018-10-26

  

  Materials and methods Author disclosure statement Acknowledgments This work was supported by the UK Medical Research Council grants G0701172 and G0801061. We thank Dr. Yacoub Khalaf, Director of the Assisted Conception Unit of Guy\'s and St Thomas\' NHS Foundation Trust and his staff for su

• enough Concurrent with the application of gene editing in hu

  2018-10-26

  

  Concurrent with the application of gene editing in human cells, the generation of human induced pluripotent stem enough (iPSCs) was described (Takahashi et al., 2007; Yu et al., 2007). iPSCs possess properties of self-renewal and pluripotency that are similar to those of embryonic stem cells (ESCs)

• br Experimental Procedures br Author Contributions br

  2018-10-26

  

  Experimental Procedures Author Contributions Acknowledgments This work is funded by the Canadian Institutes of Health Research (CIHR) (P.W.Z). E.J.P.N. is supported by a CIHR Frederick Banting and Charles Best Canada Graduate Scholarships Doctoral Award. P.W.Z. is the Canada Research Chair

• There are multiple ways whereby oxidative stress may promote

  2018-10-26

  

  There are multiple ways whereby oxidative stress may promote FOXO activation. For example, FOXO proteins can directly sense ROS through the ability of ROS to induce disulfide bridges between cysteine residues on the FOXO protein, resulting in FOXO activation and transcription of ROS-removal diazoxid

• Scanners with LIDE LED indirect exposure are an improved ver

  2018-10-26

  

  Scanners with LIDE (LED indirect exposure) are an improved version of the CIS technology. Here the light source uses powerful tri-color RGB (Red, Green, Blue) LEDs, and the radiation is directed to the object via quartz fibers ensuring uniform exposure over the entire width of the original scanner w

• br Introduction Studying the temperature dynamics of

  2018-10-26

  

  Introduction Studying the temperature dynamics of the mechanical properties of toll like receptor is important for solving the problems of cryobiology, a field concerned with the behavior of cells and tissues at low temperatures [1,2]. These properties of the plasma membrane influence the mechan

• br Assuming that we obtain and consequently br

  2018-10-26

  

  Assuming that we obtain and, consequently, Expression (3) yields the most general form of a two-dimensional harmonic function homogeneous in Euler\'s sense. Let us choose two forms for our further investigation: the symmetric and the antisymmetric. The first one is a structure of the form as

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