• The study was designed as an

  2019-04-29

  

  The study was designed as an open label, single institution phase I study at the National Heart, Lung, Blood Institute, National Institutes of Health and was approved by Institutional Review Board (NCT01629082). All patients signed an informed consent prior to enrollment and the study was conducted

• An assessment of disease risk at different life

  2019-04-29

  

  An assessment of disease risk at different life stages indicates that governmental health policies should focus on the health of young people, especially since adolescents account for nearly one fifth of the world\'s population. Although the UN General Comment 4 of the Convention on the Rights of th

• br Introduction Intrahepatic cholangiocarcinoma ICC originat

  2019-04-29

  

  Introduction Intrahepatic cholangiocarcinoma (ICC) originates from either the small intrahepatic ductules, or the large intrahepatic ducts proximal to the bifurcation of the right and left hepatic ducts. ICC accounts for 10–15% of all liver cancers, and is the second most common primary malignanc

• br Acknowledgments We thank all the ultramarathon runners wh

  2019-04-28

  

  Acknowledgments We thank all the ultramarathon runners who participated in this study and all the doctors, nurses, and emergency medical technicians who provided professional care at the ultramarathon race. We also thank our colleagues at Soochow University, Taipei, Taiwan and the Chinese Taipei

• In the case reported by

  2019-04-28

  

  In the case reported by Goldstein et al. [2], a Riata ST lead (St. Jude Medical, Sylmar, CA, USA) was used. The authors did not mention whether the lead was a dual-coil system or not. If the lead was a single-coil system, the possibility of an HV short circuit between the RV coil conductor and the d

• br The west African outbreak of Ebola

  2019-04-28

  

  The 2014–15 west African outbreak of Ebola virus disease is unprecedented in scale, especially in Sierra Leone, which as of May 15, 2015, had reported 8598 confirmed cases and 3538 confirmed Ebola-related deaths. Sierra Leone\'s response to this emergency has been compromised by a fragile health s

• Las l neas le comunican a Felipe que l y

  2019-04-28

  

  Las líneas le comunican D-Luciferin Felipe que él y sus marañones habían determinado salir De lo primero, denuncia la perversidad de la administración, encabezada por el virrey Cañete, “malo, lujurioso, ambicioso tirano”, quien “premió” a los hombres que combatieron la rebelión de Hernández Girón c

• br Although killed whole cell

  2019-04-26

  

  Although killed, whole-cell oral cholera vaccines (OCVs) have been known to be efficacious since 1986, and the bivalent whole-cell vaccine Shanchol has been licensed in India since 2009, OCV was not regarded as useful for controlling cholera outbreaks until recently. Many public health officials q

• La reivindicaci n del m rtir revolucionario El proceso del

  2019-04-26

  

  La reivindicación del mártir revolucionario El proceso del egp dio lugar secreted frizzled related protein consolidar un frente de estudiantes constituido con su línea política, trabajo continuo del estudiantado identificado con ello; respecto a la dirección de esta organización, carecemos de comun

• Podr a pensarse pues que

  2019-04-26

  

  Podría pensarse, pues, que don Melchor Carlos Inca estaba tan sólo construyendo el conveniente andamiaje discursivo y argumentativo que presentar ante el virrey condicionando una resolución favorable pannexin-1 inhibitor sus intereses. Pero entraría en juego aquí una segunda fuente a nuestra disposi

• hsp90 inhibitors On what might an argument for

  2019-04-26

  

  On what might an argument for a fairer distribution of malaria research investment rest? The investments analysed by Head and colleagues were those made from outside of sub-Saharan Africa, not by African countries themselves, and were a mix of public funds channelled through bilateral and multilater

• nitric oxide synthase inhibitors br Relationship among ICD s

  2019-04-26

  

  Relationship among ICD shocks, substrate, and mortality There is a strong correlation between ICD-shocked spontaneous VTAs and subsequent mortality [5,6]. Patients who receive inappropriate shocks are also at an increased risk of mortality, although the magnitude of this increase is smaller [5,6]

• Catheter ablation was performed from the basal septum to

  2019-04-26

  

  Catheter ablation was performed from the basal septum to the apex in the sites where the right bundle branch potential could be recorded. Radiofrequency (RF) receptor tyrosine kinase was delivered with a temperature controlled 4-mm-tip deflectable catheter (Biosense Webster, Diamond Bar, CA, USA) w

• br Approval statement br Role

  2019-04-26

  

  Approval statement Role of the funding source Conflict of interest Acknowledgments Introduction Osteosarcoma (OS) is the most common malignancy of bone, mainly affecting children, adolescents and young adults. According to the American Cancer Society, 750–900 new cases of OS are diagn

• Introduction Multiple myeloma MM is the most frequent cancer

  2019-04-26

  

  Introduction Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with 80–90% of patients developing bone lesions during their disease course [1]. Myeloma bone lesions are purely osteolytic and are associated with severe and debilitating bone pain, pathologic fractures, hyperca

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