br Introduction Stem cells are essential for tissue

2018-10-20

Introduction Stem cells are essential for tissue formation, maintenance, and repair by achieving a timely balance between error-free replicative expansion and differentiation. This balance is frequently jeopardized in cancer and aging, leading to tissue pathology and functional decline (Blanpain

br Experimental Procedures br Author Contributions

2018-10-20

Experimental Procedures Author Contributions Acknowledgments Introduction Bone marrow stromal cells (BMSCs, also called bone-marrow-derived mesenchymal stromal cells) are heterogeneous populations that likely contain varying levels of tripotent (osteogenic, adipogenic, and chondrogenic [

In mammalian PGCs genetic knockout

2018-10-20

In mammalian PGCs, genetic knockout models and short-term PGC culture experiments have implicated the growth factors BMP4, LIF, SCF, retinoic acid, and FGF in early survival and proliferation (Dolci et al., 1991, 1993; Farini et al., 2005; Matsui et al., 1991). PGCs isolated from mammalian species c

Several strategies have been recently developed

2018-10-20

Several strategies have been recently developed for CBC cell isolation via cell surface markers and fluorescence-activated cell sorting (FACS; Gracz et al., 2013; King et al., 2012; Merlos-Suarez et al., 2011; Wang et al., 2013). Although they represent considerable advances in the isolation of CBC

br Experimental Procedures br Author Contributions br

2018-10-20

Experimental Procedures Author Contributions Acknowledgments This work is supported by national Portuguese funding through FCT, Fundação para a Ciência e a Tecnologia, project UID/BIM/04773/2013 CBMR, projects PEst-OE/EQB/LA0023/2013 and PTDC/SAU-ENB/111702/2009 to J.B., U01HL100408, NIH/NH

br Results br Discussion Muscle recovery after

2018-10-20

Results Discussion Muscle recovery after traumatic injuries such as an occupational crush or blast suffered during military combat canonically induces a predisposition for additional injuries and chronic pain owing to incomplete regeneration of the tissue. Our understanding of how different fa

Hello world!

2018-07-29