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To date there are no reasonable explanations for
2018-11-01
To date, there are no reasonable explanations for the successive distribution of a lesion over the skin cleavage lines. Some scholars believed that it might involve hematogenic dissemination of somehow activated leukocytes in its pathogenesis. Others suggested that Koebner\'s phenomenon may play a p
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mm M projectile as shown in Fig a was
2018-11-01
155 mm M549 projectile, as shown in Fig. 1(a), was used as an example in the present paper. The micro-vanes were mounted at the projectile shoulder to form a new physical model, as shown in Fig. 1(b). Fig. 2 shows the computational domain of M549 projectile. Fig. 2(a) shows the grid distribution of
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br Background An existing standard
2018-11-01
Background An existing standard for description of system vulnerability analysis is the Vulnerability/Lethality (V/L) Taxonomy[2] represented in Fig. 1. Level 1 describes the initial state of thesystem before the attack. Level 2 describes the status of the components after the attack, with regard
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used by En el campo del feminismo estructuralista Patr
2018-10-31
En el campo del feminismo estructuralista, Patricia Hill Collins (2000) fue la primera en hablar de la interseccionalidad como un paradigma; sin embargo, fue Ange Marie Hancock (2007) quien propuso una formalización de este paradigma, entendido como un conjunto que engloba used by la vez teoría nor
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We speculate that viewing of contemplative architectures
2018-10-31
We speculate that histone acetyltransferase viewing of contemplative architectures may weaken the ‘narrative self’ (also referred to as intrinsic network, self-reference, or ‘Me’) while strengthening the ‘phenomenal self’ (often labeled as extrinsic network, present moment, or ‘I’) (Farb et al., 200
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Introduction Primary thyroid lymphoma is rare accounting for
2018-10-31
Introduction Primary thyroid lymphoma is rare, accounting for Methods Results Ten patients with primary thyroid lymphoma were identified. Of these, eight had DLBCL, and two had MALT lymphoma. Patient demographics, pathological diagnoses, and disease stages are listed in Table 1. In total, six
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br Conclusion br Acknowledgments This work was supported
2018-10-31
Conclusion Acknowledgments This work was supported by grants from Taipei Veterans General Hospital (V100E1-011); National Science Council (100-2321-B-010-022), and National Yang-Ming University, Ministry of Education. Introduction Laparoscopic cholecystectomy (LC) has been the treatment of
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Although bowel gas patterns may not be classical
2018-10-31
Although bowel gas patterns may not be classical, because the cecum can be displaced to any part of the abdominal cavity mimicking the sigmoid volvulus or distended stomach, cecal volvulus or cecal bascule should be considered in the differential diagnosis of patients presenting with pain, vomiting,
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hiv protease inhibitors The molecular mechanisms that are in
2018-10-31
The molecular mechanisms that are involved in inducing of alternative cell fates by increasing and reducing the amount of Sox2 during reprogramming remain unclear. An interesting finding was that Oct4 changes its partner and targets genes in a dose-dependent manner in human ESCs (Stefanovic et al.,
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A paradoxical outcome of dietary SPI exposure is
2018-10-31
A paradoxical outcome of dietary SPI exposure is the shorter latency of Wnt1-generated mammary tumors, despite the significant reduction in tumor incidence in SPI-fed mice. We previously reported that in female rats exposed to SPI and administered with the direct acting carcinogen N-methyl-nitrosour
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Many authors suggest that an increased production of ROS
2018-10-31
Many authors suggest that an increased production of ROS in the beginning of differentiation is an essential factor for adipogenesis (Liu et al., 2012; Zhou et al., 2014; Wang and Hai, 2015). ROS could, in small quantities, act in cell signaling (Mc Bride et al., 2006; Zhang and Gutterman, 2007) and
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Effective differentiation of hPSCs into DE is coupled with
2018-10-31
Effective differentiation of hPSCs into DE is coupled with the suppression of E-CADHERIN/CDH1 and pluripotency. Whereas BMP signaling has been reported to suppress E-CADHERIN/CDH1 and pluripotency (Teo et al., 2011, 2012), we observed that WNT3A is not as effective as GSK-3 inhibitors in suppressing
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Small molecules have demonstrated great potential in modulat
2018-10-31
Small molecules have demonstrated great potential in modulating cellular fate and functions. A milestone work showed that mouse iPSCs were successfully induced from mouse embryonic fibroblasts (MEF) via six chemical molecules, in the absence of Yamanaka reprogramming factors (Hou et al., 2013). Rece
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A recently developed gene editing technology
2018-10-31
A recently developed gene-editing technology using RNA-guided endonuclease (Gaj et al., 2013), which allows the desired gene to be inserted into a genomic safe harbor (GSH) area (Papapetrou et al., 2011), should be considered to avoid undesirable random genomic insertion of EOS-C(3+)-KR in the gener
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These insights into the HSC independent versus HSC
2018-10-31
These insights into the HSC-independent versus HSC-dependent immune cell reconstitution pathway in mice can be expected to affect protocols used for HSC transplantation in clinical settings. Over the past 45 years, HSC transplantation has been widely used to treat patients with cancers such as leuk
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