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Patients with heart failure are at a high risk of
2019-04-25
Patients with heart failure are at a high risk of mortality and morbidity. Medical expenses associated with heart failure are increasing, and approaches aimed at early heart failure detection and reduction of the hospitalization rate are yet to be developed. Patients with CIEDs also develop heart fa
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br Methods The prevalence of various fractionation schedules
2019-04-25
Methods The prevalence of various fractionation schedules was extracted from each of the final articles included in the review. Other relevant information, such as significant predictive factors for the use of single fraction Fmoc-Ser(tBu)-OH therapy, changes in the prevalence of fractionation s
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Introduction Bone metastases are a
2019-04-25
Introduction Bone metastases are a common manifestation of cancer [1]. Most patients present with pain and impaired mobility, while others can develop complications such as pathological fractures and telomerase inhibitors of the spinal cord or cauda equina [2]. Many randomized studies have been con
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The most compelling apparent evidence in support of the
2019-04-25
The most compelling apparent evidence in support of the depolarization hypothesis derives from the seminal studies of Nademanee et al. [129]. showing that radiofrequency ablation (RFA) of epicardial sites displaying late potentials and fractionated bipolar electrograms in the RVOT of patients with B
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br VIII Si atendemos a que
2019-04-25
VIII. Si atendemos po1 que Pablo del Prado en su Directorio espiritual, todavía en el año de 1650, incorporaba numerosas oraciones para la comunión espiritual indígena, junto a recomendaciones sobre la exclusión de la efectiva, no parece probable que se alcanzara nunca una normalización del hecho
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br Cardiac imaging br Head up tilt testing
2019-04-24
Cardiac imaging Head-up tilt testing Head-up tilt (HUT) testing is recommended to judge an episode of syncope to be likely caused by VF by excluding neurally mediated syncope (NMS). However, NMS may coexist with Brugada syndrome [42]. We conducted HUT testing in 46 patients with type-1 Brugada
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br Conclusion and future directions br Conflict of
2019-04-24
Conclusion and future directions Conflict of interest Acknowledgments Introduction Epithelial-mesenchymal transition (EMT) is a process by which epithelial focal adhesion kinase lose their polarity and are converted to a mesenchymal phenotype; recently, this has been regarded as the crit
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Preclinical studies have shown that adipocytes and MSCs
2019-04-24
Preclinical studies have shown that adipocytes and MSCs play an important role in migration and dissemination of cancer notch inhibitor [55,56]. Concerning osteosarcoma, one publication has reported that human MSCs injected through the caudal vein of mice bearing Saos-2- induced an increase in tumor
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El trasfondo musical de la
2019-04-24
El trasfondo musical de la obra de sor Juana Inés de la Cruz ha recibido la atención de connotados críticos, tanto del ámbito de la música como del de las letras. Quien parece haber inaugurado en toda forma esta veta crítica es Alfonso Méndez Plancarte en su admirable anotación de la obra de sor Jua
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Paying now rather than forever has never been
2019-04-24
Paying now rather than forever has never been as relevant as a global health solution to the HIV pandemic than in 2013. The relative success of the ongoing replenishment session for the Global Fund is a positive signal, although still insufficient considering the evidence-based targets that are set
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Do ponto de vista da insurg ncia a
2019-04-24
Do ponto de vista da insurgência, jnk inhibitor resposta governamental se encaixava perfeitamente à leitura política sustentada por Guzmán. O “presidente” pregava que a ação senderista explicitaria a violência estatal, constrangendo o campesinato a se levantar contra o Estado e em última análise, to
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Sin embargo la mayor a de los aventureros se qued
2019-04-24
Sin embargo, la mayoría de los aventureros se quedó en la ensoñación, pues no logró hacerse de caudales, ni alcanzó encomiendas; de hecho, hacia 1540 y aun años después, el número de encomenderos en el gran Perú (hoy Perú, Bolivia y Ecuador) jamás rebasó los 500, indudablemente una minoría de la pob
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India is the second largest
2019-04-23
India is the second largest consumer and third largest producer of tobacco in the world. The Indian Government has been significantly engaged in addressing the tobacco problem. A major policy, the Cigarettes and Other Tobacco Products Act (COTPA) was implemented in 2003, followed by WHO\'s Framework
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The exhibited efficacies of bone
2019-04-23
The exhibited efficacies of bone targeting treatments, in phase III clinical trials, suggest significant progress in delaying skeletal-related events, with improvements having been seen in the direct comparisons between generations of drugs. These findings also lend clear support to the utility of b
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Certainly dynamic interactions between DTCs and stromal
2019-04-23
Certainly, dynamic interactions between DTCs and stromal order EPZ-6438 within the bone microenvironment disrupt bone homeostasis, which is normally tightly controlled, to fuel metastatic progression [18] (Table 1). For example, it is well established that osteolytic breast cancer DTC-derived facto
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